11 cities
| City | Rank | 2025 Pop. ↓ | 2020 Pop. | Change | Density | Area (mi²) | Type |
|---|---|---|---|---|---|---|---|
| Cheraw | 1 | 4,972 | 5,029 | -0.22% | 835 | 5.95 | Town |
| North Hartsville | 2 | 3,264 | 1,972 | 0.03% | 721 | 4.53 | CDP |
| Pageland | 3 | 2,524 | 2,474 | 0.4% | 520 | 4.86 | Town |
| Chesterfield | 4 | 1,367 | 1,352 | 0.22% | 335 | 4.08 | Town |
| Pine Ridge | 5 | 800 | 704 | 7.1% | 353 | 2.27 | CDP |
| McBee | 6 | 798 | 770 | 0.76% | 607 | 1.31 | Town |
| Jefferson | 7 | 787 | 772 | 0.38% | 437 | 1.80 | Town |
| Cash | 8 | 521 | 298 | 7.2% | 342 | 1.52 | CDP |
| Ruby | 9 | 324 | 316 | 0.62% | 131 | 2.47 | Town |
| Patrick | 10 | 286 | 273 | 1.06% | 298 | 0.96 | Town |
| Mount Croghan | 11 | 133 | 132 | 0% | 175 | 0.76 | Town |
Cheraw is the largest city in Chesterfield County, with a population of 4,972.
Mount Croghan is the smallest city in Chesterfield County.
There are 11 cities in Chesterfield County, South Carolina.